Large thrombus in the ascending aorta successfully treated by thrombolysis - An unusual cause of acute massive myocardial infarction

H. Ito, K. Takahashi, H. Sasaki, H. Akiho, Y. Katahira, H. Saito, T. Ishibashi

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

A 52-year-old woman suffered from acute massive myocardial infarction in association with a large thrombus in the ascending aorta. She was a moderate smoker and was taking hormone supplement therapy for menopausal hormone insufficiency and the contraceptive pill for endometriosis. Cardiac angiography revealed a large mobile filling defect close to the orifice of the left coronary artery, but the left coronary artery could not be visualized. Her hemodynamic condition was impaired so greatly that intraarterial counterpulsation and intravenous thrombolysis was immediately performed. The thrombus dissolved in 1 h and recanalization of the left coronary artery was achieved without serious systemic thromboembolism. She has been doing well with no cardiac events for 7 years. This is the second report of a large thrombus in ascending aorta being the cause of acute myocardial infarction in the whole territory of the left coronary artery, and the first to diagnose such a thrombus antemortem and treat it successfully.

Original languageEnglish
Pages (from-to)572-574
Number of pages3
JournalJAPANESE CIRCULATION JOURNAL
Volume65
Issue number6
DOIs
Publication statusPublished - 2001

Keywords

  • Angiography
  • Myocardial infarction
  • Risk factors
  • Thrombolysis
  • Thrombus

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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