Laparoscopic simultaneous bilateral adrenalectomy: Assessment of feasibility and potential indications

Yoshihide Kawasaki, Shigeto Ishidoya, Yasuhiro Kaiho, Akihiro Ito, Fumitoshi Satoh, Ryo Morimoto, Haruo Nakagawa, Yoichi Arai

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Objective: To report a single-center experience with laparoscopic simultaneous bilateral adrenalectomy (LSBA) and to evaluate its safety, surgical outcomes, and potential indications of the procedure. Methods: A total of 21 patients underwent LSBA between 2000 and 2010 at our institution. Four patients had bilateral Cushing's syndrome (CS), two had bilateral pheochromocytoma, and one had a bilateral metastatic tumor. Eleven patients had unilateral or bilateral aldosterone-producing adenoma (APA), associated with CS or subclinical CS. Three patients had unilateral APA with contralateral non-functioning adenoma. Partial adrenalectomy was performed first by using with four ports. After the excision of one gland, the contralateral gland was removed after repositioning of the patient. Results: LSBA was completed in all 21 patients without major complications. Mean operative time was 329.7min and the estimated blood loss was 94.1mL. Mean tumor size was 21.8mm. Of the 16 patients receiving an adrenal-sparing procedure, nine of 11 discontinued glucocorticoid replacement after 2years. The remaining five patients receiving bilateral total adrenalectomy required 0.5-0.75mg of dexamethasone permanently. No open conversions, no deaths or no adrenal insufficiencies were encountered. Conclusions: LSBA represents a safe and viable treatment option for selected patients with bilateral adrenal disease.

Original languageEnglish
Pages (from-to)762-767
Number of pages6
JournalInternational Journal of Urology
Issue number11
Publication statusPublished - 2011 Nov


  • Bilateral adrenalectomy
  • Laparoscopy
  • Partial adrenalectomy
  • Primary hyperaldosteronism
  • Steroid replacement

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Laparoscopic simultaneous bilateral adrenalectomy: Assessment of feasibility and potential indications'. Together they form a unique fingerprint.

Cite this