Langmuir-blodgett films in advanced molecular engineering

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13 Citations (Scopus)

Abstract

Recent developments in characterization of Langmuir-Blodgett (LB) films have enabled us to design and study functionalized monolayers at the molecular level. Highly sophisticated molecular recognition systems have been developed using LB films. Monolayers at the air/water interface provide a unique environment for molecular recognition. We have developed new host-guest systems in which such monolayers bind water-soluble substances selectively through hydrogen bonding. Monolayers have been functionalized at their hydrophilic groups with diaminotriadine, urea, orotate, Kemp's acid, guanidinium and resorcinol groups. Polar substrates such as nucleobases, nitrogen aromatics, amino acids, AMP, ATP and sugars have been found to bind to these monolayers efficiently from the aqueous subphase. They have association constants which are comparable to those reported for similar systems in aprotic solvents. This is in contrast to the generally held view that the interaction in simple organic receptors is suppressed in the aqueous micro-environment, and should be brought out from unique properties of monolayer surfaces. Molecular recognition of monolayer hosts exhibits various specific features owing to two-dimensional organization of binding sites at the air/water interface.

Original languageEnglish
Pages (from-to)425-432
Number of pages8
JournalColloids and Surfaces A: Physicochemical and Engineering Aspects
Volume123-124
DOIs
Publication statusPublished - 1997 May 15
Externally publishedYes

Keywords

  • Functionalized monolayers
  • Host-Guest systems
  • Langmuir-Blodgett films
  • Molecular recognition

ASJC Scopus subject areas

  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

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