Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Hideaki Uchida; Yasushi Kawai; Hideki Kinoshita; Haruki Kitazawa; Koh Miura; Kenichi Shiiba; Akira Horii; Katsunori Kimura; Naoki Taketomo; Munehiro Oda; Takaji Yajima; Tadao Saito

doi:10.1271/bbb.60407

Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Hideaki Uchida, Yasushi Kawai, Hideki Kinoshita, Haruki Kitazawa, Koh Miura, Kenichi Shiiba, Akira Horii, Katsunori Kimura, Naoki Taketomo, Munehiro Oda, Takaji Yajima, Tadao Saito

AGR - Agricultural Bioscience

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galα1-3 (Fucα1-2) Gal-] and H-antigen (Fucα1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.

Original language	English
Pages (from-to)	3073-3076
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	70
Issue number	12
DOIs	https://doi.org/10.1271/bbb.60407
Publication status	Published - 2006

Keywords

Adherence
Human B-antigen
Human H-antigen
Lactic acid bacteria
Surface plasmon resonance

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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10.1271/bbb.60407

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title = "Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa",

abstract = "Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galα1-3 (Fucα1-2) Gal-] and H-antigen (Fucα1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.",

keywords = "Adherence, Human B-antigen, Human H-antigen, Lactic acid bacteria, Surface plasmon resonance",

author = "Hideaki Uchida and Yasushi Kawai and Hideki Kinoshita and Haruki Kitazawa and Koh Miura and Kenichi Shiiba and Akira Horii and Katsunori Kimura and Naoki Taketomo and Munehiro Oda and Takaji Yajima and Tadao Saito",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (B) (no. 16380179) and by a Grant-in-Aid for Exploratory Research (no. 00118358) from the Japanese Ministry of Education, Culture, Sports,",

year = "2006",

doi = "10.1271/bbb.60407",

language = "English",

volume = "70",

pages = "3073--3076",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "12",

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TY - JOUR

T1 - Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

AU - Uchida, Hideaki

AU - Kawai, Yasushi

AU - Kinoshita, Hideki

AU - Kitazawa, Haruki

AU - Miura, Koh

AU - Shiiba, Kenichi

AU - Horii, Akira

AU - Kimura, Katsunori

AU - Taketomo, Naoki

AU - Oda, Munehiro

AU - Yajima, Takaji

AU - Saito, Tadao

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (B) (no. 16380179) and by a Grant-in-Aid for Exploratory Research (no. 00118358) from the Japanese Ministry of Education, Culture, Sports,

PY - 2006

Y1 - 2006

N2 - Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galα1-3 (Fucα1-2) Gal-] and H-antigen (Fucα1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.

AB - Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galα1-3 (Fucα1-2) Gal-] and H-antigen (Fucα1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.

KW - Adherence

KW - Human B-antigen

KW - Human H-antigen

KW - Lactic acid bacteria

KW - Surface plasmon resonance

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U2 - 10.1271/bbb.60407

DO - 10.1271/bbb.60407

M3 - Article

C2 - 17151450

AN - SCOPUS:33845889108

VL - 70

SP - 3073

EP - 3076

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 12

ER -

Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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