Lactic acid bacteria (LAB) bind to human B- or H-antigens expressed on intestinal mucosa

Hideaki Uchida, Yasushi Kawai, Hideki Kinoshita, Haruki Kitazawa, Koh Miura, Kenichi Shiiba, Akira Horii, Katsunori Kimura, Naoki Taketomo, Munehiro Oda, Takaji Yajima, Tadao Saito

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Twenty lactobacilli isolated from human feces were studied for binding to the human blood type B-antigen [Galα1-3 (Fucα1-2) Gal-] and H-antigen (Fucα1-2Gal-] expressed sugar chains in human intestinal mucosa. We found two strains, L. gasseri OLL2755 and L. gasseri OLL2877 that firmly adhere to human B-antigen, and we found L. gasseri OLL2827 bound to the H-antigen.

Original languageEnglish
Pages (from-to)3073-3076
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number12
DOIs
Publication statusPublished - 2006

Keywords

  • Adherence
  • Human B-antigen
  • Human H-antigen
  • Lactic acid bacteria
  • Surface plasmon resonance

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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