HEK293 cells transfected with a double-stranded siRNA to suppress expression of the homeobox gene HOXB13 were highly resistant to oxidative stress-inducing agents, such as hydrogen peroxide, A-ethylmaleimide (NEM), and paraquat. This finding suggests that HOXB13 might enhance cell injury caused by oxidative stress.
|Number of pages||2|
|Journal||Journal of Toxicological Sciences|
|Publication status||Published - 2013|
- Homeobox gene
- Oxidative stress
ASJC Scopus subject areas