Keratoacanthoma Centrifugum Marginatum with Spontaneous Regression and Its Possible Differential Diagnosis

Ryo Amagai, Taku Fujimura, Yumi Kambayashi, Sadanori Furudate, Yota Sato, Kayo Tanita, Akira Hashimoto, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Keratoacanthoma centrifugum marignatum (KCM) is a rare variant of keratoacanthoma, which is characterized by the dense infiltration of inflammatory cells throughout the dermis, especially around the keratinocytic islands. Therefore, it is sometimes difficult to differentiate between KCM and cutaneous T-cell lymphomas. In this report, we describe a case of KCM with spontaneous regression that showed dense infiltration of CD3+CD8+ T cells. Our present case suggested the importance of investigating tumor-infiltrating lymphocytes to avoid the misdiagnosis of KCM as cutaneous T-cell lymphoma.

Original languageEnglish
Pages (from-to)671-675
Number of pages5
JournalCase Reports in Oncology
Volume11
Issue number3
DOIs
Publication statusPublished - 2018 Sep 1

Keywords

  • Cutaneous T-cell lymphoma
  • Keratoacanthoma centrifugum marginatum
  • Spontaneous regression
  • Tumor-infiltrating lymphocytes

ASJC Scopus subject areas

  • Oncology

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