Japan pancreatic cancer registry; 30th year anniversary: Japan pancreas society

Shinichi Egawa, Hiroki Toma, Hiroaki Ohigashi, Takuji Okusaka, Akimasa Nakao, Takashi Hatori, Hiroyuki Maguchi, Akio Yanagisawa, Masao Tanaka

Research output: Contribution to journalReview articlepeer-review

177 Citations (Scopus)

Abstract

OBJECTIVES: Since 1981, the Japan Pancreas Society has been hosting a nationwide pancreatic cancer registry. To commemorate its 30th anniversary, we review its history and latest achievement. METHODS: During 3 decades, more than 350 leading institutions in Japan contributed voluntarily to register and periodic follow-up. The registry was modified to protect privacy by encrypting and hash algorithm. RESULTS: From 1981 to 2007, 32,619 cumulative records were analyzed. The overall survival of invasive cancer was improved significantly. More patients with earlier stage or with intraductal and cystic neoplasms underwent resection. The strongest prognostic factor of Union for International Cancer Control (UICC) stage IIA and IIB tubular adenocarcinoma in the pancreatic head was histological grade, followed by tumor size, extent of lymph node dissection, and postoperative chemotherapy. The 5-year survival rate of Union for International Cancer Control stage 0 reached 85%. The improvement of survival of patients with invasive cancer in Japan can be attributed to the introduction of effective chemotherapies, regionalization, and the earlier diagnosis and treatment. Simple definition of "early pancreatic cancer" is needed. CONCLUSIONS: At the 30th year anniversary, the Japan Pancreas Society nationwide pancreatic cancer registry is more shining than ever for current perspectives and for future diagnostic and treatment tactics.

Original languageEnglish
Pages (from-to)985-992
Number of pages8
JournalPancreas
Volume41
Issue number7
DOIs
Publication statusPublished - 2012 Oct

Keywords

  • adjuvant therapy
  • classification
  • early diagnosis
  • nationwide registry
  • pancreatic cancer
  • surgical treatment

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Fingerprint Dive into the research topics of 'Japan pancreatic cancer registry; 30th year anniversary: Japan pancreas society'. Together they form a unique fingerprint.

Cite this