Isothermal amplification of specific DNA molecules inside giant unilamellar vesicles

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

An isothermal amplification circuit for specific DNA molecules was implemented in giant unilamellar vesicles. Using this circuit, over 5000-fold amplification of output DNAs was achieved, and the amplification behaviour depended on the concentration of input signal DNAs in a cell-sized compartment. Moreover, initiation of the amplification by photo-stimulation was demonstrated.

Original languageEnglish
Pages (from-to)9084-9087
Number of pages4
JournalChemical Communications
Volume55
Issue number62
DOIs
Publication statusPublished - 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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