Isolation and characterization of hemagglutinins from the sponge Dysidea herbacea

H. Kamiya, Koji Muramoto, T. Hoshino, U. Raj

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)

    Abstract

    The sponge Dysidea herbacea (Keller) was found to possess hemagglutinins. The major component, DHA-I, is a protein with a mol.wt of 26,000, which dissociates into subunits of equal size (14,000). It contains large amounts of glutamic acid and aspartic acid residues, but no half-cystine, methionine or histidine residues. DHA-I reacted with rabbit and human AB0 erythrocytes. D-galactose and lactose were effective inhibitors of DHA-I. The sponge also contained a minor component(s) which reacted preferentially with rabbit erythrocytes but not with human AB0 erythrocytes.

    Original languageEnglish
    Pages (from-to)1201-1202
    Number of pages2
    JournalExperientia
    Volume41
    Issue number9
    DOIs
    Publication statusPublished - 1985 Sep 1

    Keywords

    • Dysidea herbacea
    • Hemagglutinin
    • agglutinin
    • lectin
    • sponge

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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