Iron nanoparticles-encapsulating silica microspheres for arterial embolization hyperthermia

Z. Li, M. Kawashita

Research output: Contribution to journalConference articlepeer-review


We attempted to prepare α-Fe-encapsulating silica (αFeSi) microspheres by a sol-gel process using tetramethoxysilane (TMOS) in water-in-oil emulsion. The effect of preparation conditions on the structure, magnetic and heating properties of resultant products were investigated. Oil phase consisted of kerosene with 32 wt% of surfactants (sorbitan monooleate/sorbitan monostearate in 3:1 weight ratio). Water phase consisted of TMOS, ethanol (CH2CH3OH), water and iron nitrate (Fe(NO3)39H2O) with TMOS / CH 2CH3OH/H2O/Fe3+ in 1:7.4:16.2:0.4∼1.2 molar ratio. Fe3+-containing silica gel (FeSiG) microspheres 5 to 30 μm in size were successfully obtained by adding the water phase into the oil phase at 60 °C under stirring of 1500 rpm for 100 min. αFeSi microspheres was obtained by heating the FeSiG microspheres at 850°C in argon atmosphere. The obtained αFeSi microspheres have a saturation magnetization (Ms) up to 21 emu g-1 and a coercive force (Hc) of 133 Oe. The in vitro heating generation was evaluated under an alternating current (AC) magnetic field of 300 Oe and 100 kHz.

Original languageEnglish
Article number192005
JournalIOP Conference Series: Materials Science and Engineering
Issue numberSYMPOSIUM 13
Publication statusPublished - 2011 Aug 31
Event3rd International Congress on Ceramics, ICC3 - Osaka, Japan
Duration: 2010 Nov 142010 Nov 18

ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)


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