Ion channels in calcitonin-secreting cells of the chick

K. Kawa

Research output: Contribution to journalArticlepeer-review

Abstract

Calcitonin-secreting cells were isolated from ultimobranchial gland of the chick embryos (18-20 days after fertilization). Using whole-cell patch electrode, the membrane currents of the dissociated cells were recorded. With depolarization, tetrodotoxin-sensitive Na+ current was produced which was followed by slowly developing outward K+ current. These cells were positively stained with anticalcitonin antibody (#7701R1) raised in the rabbit. In some cells, no measurable Na+ currents were evoked and the stainings with the antibody were faint or negative.

Original languageEnglish
Pages (from-to)87-88
Number of pages2
JournalBiomedical Research
Volume9
Issue numberSUPPL. 2
Publication statusPublished - 1988 Jan 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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