Investigation of blood compatibility for cytocompatibility type a-C:H films

Yasuharu Ohgoe, Yasuyuki Shiraishi, Hidekazu Miura, Kenji Hirdkuri, Akio Fimakiibo, Tomoyuki Yarrbe, Yasuhiro Fiikiii

Research output: Contribution to journalArticle

Abstract

In this study, in order to investigate blood compatibility of cytooompatibility type hydrogenated amorphous carbon (a-C:H) film, the a-C:H film coated segmented polyurethane (SPU) scaffold fiber sheet (a-CJf-Scaffold) was implanted at partial aorta desoendens of a goat for 35 days. The scatfold sheet was fabricated by electronspirming method, and the a-C:H film was deposited on the scaffold sheet by nf plasma chemical vapor deposition (CVD) technique. In in-iiw test, it was observed that the a-C.H film ooating surface was uniformly covered by neointima Additionally, the surface had no thrombus formation as an inflammatory reaction and it was shown that tlie a-C:H film coating had a good blood compatibility. These results suggest thatcytooompatibility type a-C:H film lias emetgedasa potential technique for blood interfacing applications.

Original languageEnglish
Pages (from-to)O-204-O-205
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume52
DOIs
Publication statusPublished - 2014 Aug 17

Keywords

  • A-C:H film
  • Blood compatibility
  • Cell growth

ASJC Scopus subject areas

  • Biomedical Engineering

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