Investigation for analytical procedure for determination of trace metallic ions in simulated body fluids by inductively coupled plasma atomic emission spectrometry (ICP-AES)

Naofumi Ohtsu, Tetsuya Ashino, Hisamichi Kimura, Kunio Takada, Takao Hanawa

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Influences of matrix elements and high viscosity in three kind of simulated body fluids (SBFs) on determination of trace metallic elements (Co, Cr, Ni, Al and V) by inductively coupled plasma atomic emission spectrometry (ICP-AES) were investigated. In addition, decreases of these effects were attempted by H 2SO4 fume treatment. Calibration lines of the elements were constructed by the standard solutions made of elemental solutions and HCl or the SBFs. Gradients of calibration lines constructed by the each standard solution were different. Therefore, for accurate determination, calibration curve must be constructed by the elemental standard solution and the analytical solution. Limit of detection (LOD) of each element in the solutions was measured by a blank test. Although LODs of μg·L-1 (ppb) order were nominal instrumental data, because of influences of the matrix elements and the high viscosity, the measured LODs of the elements in the SBFs were higher than those. However, the LODs were lowered by employing the H2SO 4-fume treatment and approached to the nominal instrumental data. Therefore, H2SO4-fume treatment is extremely effective treatment in order to reduce the influences.

Original languageEnglish
Pages (from-to)429-433
Number of pages5
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number3
DOIs
Publication statusPublished - 2007 Mar 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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