Intravenous contrast echocardiography

T. Masuyama, K. Yamamoto, H. Kondo, N. Nishikawa, Y. Sakata, K. Ono, T. Kuzuya, M. Hori

Research output: Contribution to journalArticlepeer-review


Intravenous contrast echocardiography has become possible in Japan because of the release of the commercially available contrast agent, Levovist. Intravenous administration of Levovist satisfactorily stains the left ventricular cavity, which makes it possible to clearly delineate the endocardial borden. Clear delineation of the endocardial border provides easy and accurate measurement of left ventricular dimension and wall thickness, and wall motion abnormalities can be easily and accurately judged, too. Another benefit of intravenous contrast echocardiography is the assessment of myocardial perfusion. Our preliminary experimental and clinical experiences showed the possibility of myocardial staining with intravenous contrast echocardiography. Impressive myocardial staining is obtainable with the combined use of intermittent and contrast harmonic power Doppler imaging. In order to obtain reproducible and clear myocardial contrast images, we have to pay attention to how to inject contrast and settings of ultrasound equipment, i. e., mechanical index, gain setting, depth of focus point, and pulse repetition frequency, artifacts. In the near future, a lot of issues should be standardized to make it possible to compare myocardial contrast echo studies.

Original languageEnglish
Pages (from-to)23-29
Number of pages7
JournalJournal of cardiology
Issue numberSUPPL. I
Publication statusPublished - 2000 May 16
Externally publishedYes


  • Contrast echocardiography (harmonic imaging)
  • Coronary artery disease
  • Doppler ultrasound
  • Echocardiography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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