Intraoperative radiation therapy and chemotherapy for huge choroid plexus carcinoma in an infant - Case report

Toshihiro Kumabe, Teiji Tominaga, Takeo Kondo, Takashi Yoshimoto, Takamasa Kayama

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

A 2-month-old boy presented with a huge choroid plexus carcinoma in the left cerebral hemisphere. Almost total resection of the tumor was achieved, but a remnant abruptly enlarged 5 months later, requiring reoperation. After radical resection of the tumor, intraoperative radiation (10 Gy) was delivered. Postoperative chemotherapy was performed with methotrexate and vincristine, selected on the basis of in vitro chemosensitivity testing. No recurrence of the tumor was detected 18 months after the second operation. Radical surgery with these adjuvant therapies may be a good method to control this aggressive disease in infants.

Original languageEnglish
Pages (from-to)179-184
Number of pages6
JournalNeurologia medico-chirurgica
Volume36
Issue number3
DOIs
Publication statusPublished - 1996 Mar

Keywords

  • chemosensitivity test
  • chemotherapy
  • choroid plexus carcinoma
  • intraoperative radiation therapy
  • magnetic resonance imaging
  • operation

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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