Intramolecular C-N bond addition of amides to alkynes using platinum catalyst

Tomohiro Shimada, Itaru Nakamura, Yoshinori Yamamoto

Research output: Contribution to journalArticle

176 Citations (Scopus)

Abstract

The intramolecular aminoacylation of alkynes using ortho-alkynylacetanilides proceeds in very high yields in the presence of PtCl2 catalyst. This reaction provides not only a useful procedure for synthesizing 2,3-disubstituted indoles at once from ortho-alkynylaniline derivatives, but also an interesting mechanistic aspect; the intramolecular C-N bond addition of amides to alkynes takes place readily in the presence of Pt(II) catalyst.

Original languageEnglish
Pages (from-to)10546-10547
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number34
DOIs
Publication statusPublished - 2004 Sep 1

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Intramolecular C-N bond addition of amides to alkynes using platinum catalyst'. Together they form a unique fingerprint.

  • Cite this