Abstract
A 61-year-old man was implanted with a Jarvik 2000, a continuous axial flow type left ventricular assist device (LVAD), for end-stage heart failure due to dilated cardiomyopathy. One month later, his postoperative course was complicated with intractable oozing-type gastrointestinal bleeding from multiple small shallow ulcers and erosions in the colon. In addition, repeated bleeding episodes were encountered at around thoracentesis site for pleural effusion. Hematological examination showed that platelet counts and coagulation factors were kept within normal ranges. We, thereafter, revealed remarkable loss of the large multimers of von Willebrand factors (VWFs), which might be closely associated with his intractable bleeding tendency.
Original language | English |
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Pages (from-to) | 289-292 |
Number of pages | 4 |
Journal | Journal of Artificial Organs |
Volume | 19 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2016 Sep 1 |
Keywords
- Acquired von Willebrand syndrome
- Bleeding tendency
- Ventricular assist device
- Von Willebrand factors
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Biomaterials
- Biomedical Engineering
- Cardiology and Cardiovascular Medicine