Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm

Masayuki Ezura; Akira Takahashi; Kuniaki Ogasawara; Takashi Yoshimoto

doi:10.1016/S0090-3019(96)00247-9

Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm

Masayuki Ezura, Akira Takahashi, Kuniaki Ogasawara, Takashi Yoshimoto

MEN - Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

BACKGROUND: This 42-year-old male presented with subarachnoid hemorrhage of Hunt and Kosnik Grade IV, complicated by neurogenic pulmonary edema, prolongation of the electrocardiographic Q-Q interval, and acute renal failure. METHODS: Surgical clipping was not indicated, so intra-aneurysmal embolization using Guglielmi detachable coils (GDCs) was performed followed by intrathecal infusion of tissue-type plasminogen activator (tPA) via spinal drainage. RESULTS: The patient made a complete recovery 2 1/4 months later except for partial third cranial nerve palsy. CONCLUSIONS: Intra-aneurysmal GDC embolization followed by intrathecal tPA via spinal drainage is an excellent method for treating aneurysms that are difficult to treat surgically.

Original language	English
Pages (from-to)	144-147
Number of pages	4
Journal	Surgical Neurology
Volume	47
Issue number	2
DOIs	https://doi.org/10.1016/S0090-3019(96)00247-9
Publication status	Published - 1997 Feb

Keywords

Basilar artery aneurysm
detachable coils
embolization
poor grade
spinal drainage
tissue type plasminogen activator

ASJC Scopus subject areas

Surgery
Clinical Neurology

Access to Document

10.1016/S0090-3019(96)00247-9

Cite this

@article{4816760a593b43d7b6d9d11107a7b682,

title = "Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm",

abstract = "BACKGROUND: This 42-year-old male presented with subarachnoid hemorrhage of Hunt and Kosnik Grade IV, complicated by neurogenic pulmonary edema, prolongation of the electrocardiographic Q-Q interval, and acute renal failure. METHODS: Surgical clipping was not indicated, so intra-aneurysmal embolization using Guglielmi detachable coils (GDCs) was performed followed by intrathecal infusion of tissue-type plasminogen activator (tPA) via spinal drainage. RESULTS: The patient made a complete recovery 2 1/4 months later except for partial third cranial nerve palsy. CONCLUSIONS: Intra-aneurysmal GDC embolization followed by intrathecal tPA via spinal drainage is an excellent method for treating aneurysms that are difficult to treat surgically.",

keywords = "Basilar artery aneurysm, detachable coils, embolization, poor grade, spinal drainage, tissue type plasminogen activator",

author = "Masayuki Ezura and Akira Takahashi and Kuniaki Ogasawara and Takashi Yoshimoto",

year = "1997",

month = feb,

doi = "10.1016/S0090-3019(96)00247-9",

language = "English",

volume = "47",

pages = "144--147",

journal = "World Neurosurgery",

issn = "1878-8750",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm

AU - Ezura, Masayuki

AU - Takahashi, Akira

AU - Ogasawara, Kuniaki

AU - Yoshimoto, Takashi

PY - 1997/2

Y1 - 1997/2

N2 - BACKGROUND: This 42-year-old male presented with subarachnoid hemorrhage of Hunt and Kosnik Grade IV, complicated by neurogenic pulmonary edema, prolongation of the electrocardiographic Q-Q interval, and acute renal failure. METHODS: Surgical clipping was not indicated, so intra-aneurysmal embolization using Guglielmi detachable coils (GDCs) was performed followed by intrathecal infusion of tissue-type plasminogen activator (tPA) via spinal drainage. RESULTS: The patient made a complete recovery 2 1/4 months later except for partial third cranial nerve palsy. CONCLUSIONS: Intra-aneurysmal GDC embolization followed by intrathecal tPA via spinal drainage is an excellent method for treating aneurysms that are difficult to treat surgically.

AB - BACKGROUND: This 42-year-old male presented with subarachnoid hemorrhage of Hunt and Kosnik Grade IV, complicated by neurogenic pulmonary edema, prolongation of the electrocardiographic Q-Q interval, and acute renal failure. METHODS: Surgical clipping was not indicated, so intra-aneurysmal embolization using Guglielmi detachable coils (GDCs) was performed followed by intrathecal infusion of tissue-type plasminogen activator (tPA) via spinal drainage. RESULTS: The patient made a complete recovery 2 1/4 months later except for partial third cranial nerve palsy. CONCLUSIONS: Intra-aneurysmal GDC embolization followed by intrathecal tPA via spinal drainage is an excellent method for treating aneurysms that are difficult to treat surgically.

KW - Basilar artery aneurysm

KW - detachable coils

KW - embolization

KW - poor grade

KW - spinal drainage

KW - tissue type plasminogen activator

UR - http://www.scopus.com/inward/record.url?scp=0031026802&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031026802&partnerID=8YFLogxK

U2 - 10.1016/S0090-3019(96)00247-9

DO - 10.1016/S0090-3019(96)00247-9

M3 - Article

C2 - 9040817

AN - SCOPUS:0031026802

VL - 47

SP - 144

EP - 147

JO - World Neurosurgery

JF - World Neurosurgery

SN - 1878-8750

IS - 2

ER -

Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this