Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm

Masayuki Ezura, Akira Takahashi, Kuniaki Ogasawara, Takashi Yoshimoto

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

BACKGROUND: This 42-year-old male presented with subarachnoid hemorrhage of Hunt and Kosnik Grade IV, complicated by neurogenic pulmonary edema, prolongation of the electrocardiographic Q-Q interval, and acute renal failure. METHODS: Surgical clipping was not indicated, so intra-aneurysmal embolization using Guglielmi detachable coils (GDCs) was performed followed by intrathecal infusion of tissue-type plasminogen activator (tPA) via spinal drainage. RESULTS: The patient made a complete recovery 2 1/4 months later except for partial third cranial nerve palsy. CONCLUSIONS: Intra-aneurysmal GDC embolization followed by intrathecal tPA via spinal drainage is an excellent method for treating aneurysms that are difficult to treat surgically.

Original languageEnglish
Pages (from-to)144-147
Number of pages4
JournalSurgical Neurology
Volume47
Issue number2
DOIs
Publication statusPublished - 1997 Feb

Keywords

  • Basilar artery aneurysm
  • detachable coils
  • embolization
  • poor grade
  • spinal drainage
  • tissue type plasminogen activator

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Intra-aneurysmal GDC embolization followed by intrathecal tPA administration for poor-grade basilar tip aneurysm'. Together they form a unique fingerprint.

Cite this