Interferon Induction in Murine Peritoneal Macrophage by Stimulation with Lactobacillus acidophilus

Haruki Kitazawa, Takatoshi FroH, Kazuki Matsumura, Takahiro Yamaguchi

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Induction of interferon for a kind of dairy lactic acid bacteria, Lactobacillus acidophilus (L. acidophilus), was investigated in murine peritoneal macrophage (Mcb) cultures. Lactobacillus acidophilus JCM 1034, 1132T, 1229 and 2125 induced IFN (12–34 I.U./m1) in MO cultures in vitro. Strain 1132T- and 2125-induced IFNs were characterized as IFNo183 by treatment with anti-IFNs serum. The results indicate that the inducing activity of IFNs may be one of the available biological parameters for designating the dairy products containing L. acidophilus as “physiologically functional foods.”.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalMICROBIOLOGY and IMMUNOLOGY
Volume36
Issue number3
DOIs
Publication statusPublished - 1992 Jan 1

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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