Abstract
1,3-Bis(O-cyanomethyl)-p-tert-butylthiacalix[4]arene (5) has been found to interconvert between syn and anti conformations in solution. The equilibrium shifts toward the anti form with increasing solvent polarity. In the solid state, it adopts a pinched cone conformation with the syn arrangement of the cyanomethyl groups. Reduction of the equilibrium mixture of 5 with LiAlH 4 gives only anti stereoisomer of 1,3-bis(O-amino-ethyl)-p-tert- butylthiacalix[4]arene.
Original language | English |
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Pages (from-to) | 184-185 |
Number of pages | 2 |
Journal | Chemistry Letters |
Volume | 33 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2004 Feb 5 |
ASJC Scopus subject areas
- Chemistry(all)