Interaction of Er:YAG laser radiation with ureter tissue

Helena Jelínková, Petr Koranda, Michal Němec, Jan Šulc, Oto Köhler, Pavel Drlík, Mitsunobu Miyagi, Yi Wei Shi, Yuji Matsuura

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)

Abstract

The aim of the work was to investigate the possibility of the ureter wall perforation by Er:YAG laser radiation and to explore the basic interaction characteristics for ureter surface and its deep structures. For these experiments Er:YAG laser system (wavelength 2.94 μm) working in free-running and Q-switched regime was utilized. Laser radiation was delivered to the investigated tissue by a special waveguide system. The basic part was a cyclic olefin polymer-coated silver hollow glass waveguide (inner/outer diameter 700/850/μm or 320/450/μm). Sealed cap of the waveguide was used for contact treatment. Maximum interaction pulse energy and length for free-running Er:YAG I laser with the 700 μm waveguide were 100 mJ and 200 μs, respectively (corresponding intensity was 130kW/cm2). Similarly the maximum interaction pulse energy and length for free-running Er:YAG II laser with the 320 um waveguide were 80 mJ and 200 μs, respectively (corresponding intensity was 500kW/cm2). Maximum interaction pulse energy and length in Q-switched regime were 17 mJ and 70ns, respectively (corresponding intensity 63MW/cm2). The number of pulses needed to perforate the ureter wall tissue (thickness ∼ 1 mm) for using long 200 μs Er:YAG pulses (thermal ablation) and short 70 ns Er:YAG pulses (photoablation) was found. From the histological evaluation it follows that the application of Q-switched Er:YAG laser radiation on ureteral tissue resulted in minimum adjacent tissue alteration (up to 50 μm from the surface) without any influence on the deeper layers.

Original languageEnglish
Article number59680A
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5968
DOIs
Publication statusPublished - 2005 Dec 1
EventLaser Florence 2004: A Window on the Laser Medicine World - Florence, Italy
Duration: 2004 Oct 282004 Oct 30

Keywords

  • Er:YAG laser
  • Hollow waveguide
  • Incision
  • Q-switching
  • Ureter
  • Urology application

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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