TY - JOUR
T1 - Instantaneous acceleration and amplification of hippocampal theta wave coincident with phasic pontine activities during REM sleep
AU - Karashima, Akihiro
AU - Nakao, Mitsuyuki
AU - Katayama, Norihiro
AU - Honda, Kazuki
N1 - Funding Information:
This work was partly supported by the “Academic Frontiers” Project for Private Universities (the Kansei Fukushi Research Center of Tohoku Fukushi University): matching fund subsidy and a Grant-in-Aid for Scientific Research (No.17605001) from the Ministry of Education, Culture, Sports, Science and Technology of Japan (2004–2008). This research was also supported by the Collaborative Research in Center for Interdisciplinary Research, Tohoku University.
PY - 2005/7/27
Y1 - 2005/7/27
N2 - Rapid eye movement (REM) sleep is characterized by hippocampal theta waves and phasic spike-like waves originating from the pons, termed ponto-geniculo-occipital (PGO) waves in cats and pontine (P) waves in rats. While the theta wave and PGO/P wave have been suggested to participate in higher-order brain functions, their generation mechanisms and roles in brain functions have been studied independently. Therefore, the present study investigated instantaneous aspects of the relationship between theta waves and PGO/P waves in both cats and rats. Theta wave was instantaneously accelerated several hundred milliseconds before the negative peak of the PGO/P wave in both animals, and was also amplified just before PGO/P wave occurrence. Considering the integrated knowledge provided by studies of both animals, these results suggest that PGO/P wave-related activities in the pons are delivered to the theta wave generator. The activations of the theta wave coincident with PGO/P wave might facilitate cooperative contribution to higher-order brain functions in REM sleep.
AB - Rapid eye movement (REM) sleep is characterized by hippocampal theta waves and phasic spike-like waves originating from the pons, termed ponto-geniculo-occipital (PGO) waves in cats and pontine (P) waves in rats. While the theta wave and PGO/P wave have been suggested to participate in higher-order brain functions, their generation mechanisms and roles in brain functions have been studied independently. Therefore, the present study investigated instantaneous aspects of the relationship between theta waves and PGO/P waves in both cats and rats. Theta wave was instantaneously accelerated several hundred milliseconds before the negative peak of the PGO/P wave in both animals, and was also amplified just before PGO/P wave occurrence. Considering the integrated knowledge provided by studies of both animals, these results suggest that PGO/P wave-related activities in the pons are delivered to the theta wave generator. The activations of the theta wave coincident with PGO/P wave might facilitate cooperative contribution to higher-order brain functions in REM sleep.
KW - Hippocampal theta wave
KW - Pontine wave
KW - Ponto-geniculo-occipital wave
KW - REM sleep
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U2 - 10.1016/j.brainres.2005.05.055
DO - 10.1016/j.brainres.2005.05.055
M3 - Article
C2 - 15982642
AN - SCOPUS:22144436307
VL - 1051
SP - 50
EP - 56
JO - Molecular Brain Research
JF - Molecular Brain Research
SN - 0006-8993
IS - 1-2
ER -