Instantaneous acceleration and amplification of hippocampal theta wave coincident with phasic pontine activities during REM sleep

Akihiro Karashima, Mitsuyuki Nakao, Norihiro Katayama, Kazuki Honda

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Rapid eye movement (REM) sleep is characterized by hippocampal theta waves and phasic spike-like waves originating from the pons, termed ponto-geniculo-occipital (PGO) waves in cats and pontine (P) waves in rats. While the theta wave and PGO/P wave have been suggested to participate in higher-order brain functions, their generation mechanisms and roles in brain functions have been studied independently. Therefore, the present study investigated instantaneous aspects of the relationship between theta waves and PGO/P waves in both cats and rats. Theta wave was instantaneously accelerated several hundred milliseconds before the negative peak of the PGO/P wave in both animals, and was also amplified just before PGO/P wave occurrence. Considering the integrated knowledge provided by studies of both animals, these results suggest that PGO/P wave-related activities in the pons are delivered to the theta wave generator. The activations of the theta wave coincident with PGO/P wave might facilitate cooperative contribution to higher-order brain functions in REM sleep.

Original languageEnglish
Pages (from-to)50-56
Number of pages7
JournalBrain research
Volume1051
Issue number1-2
DOIs
Publication statusPublished - 2005 Jul 27

Keywords

  • Hippocampal theta wave
  • Pontine wave
  • Ponto-geniculo-occipital wave
  • REM sleep

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Instantaneous acceleration and amplification of hippocampal theta wave coincident with phasic pontine activities during REM sleep'. Together they form a unique fingerprint.

  • Cite this