A pair of musical instruments named "Cosmical Seeds" suitable for weightlessness, was selected by the Japan Aerospace Exploration Agency (JAXA) to represent the theme of Cultural and Artistic Utilization of the International Space Station (ISS). The instruments were successfully launched on October 31, 2011; and NASA astronaut Daniel C. Burbank, Expedition 30 commander, operated and played the instruments on the ISS on February 10, 2012. The two pieces of music performed were a collaboration between an astronaut and ambient music specialists Akira Takahashi and Jaakko Saari. This paper will present: Motivation which led to the creation of the musical instruments The concept of the project The results of parabolic flight testing The results of the mission at the ISS Future possibilities The astronaut played the instruments along with music repeatedly for 15 minutes and improved his skills beyond what was outlined in the procedure manual. Taking movies and audio recordings was very successful, and the video will be shown at this session.