Inhibition and acclimation of nitrifiers exposed to erythromycin

Jingru Du, Weikang Qi, Qigui Niu, Yong Hu, Yu Zhang, Min Yang, Yu You Li

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The influence of erythromycin on ammonia-oxidizing bacteria (AOB) and nitrite-oxidizing bacteria (NOB) was investigated using batch and continuous experiments. During the batch experiments, the impact of erythromycin was strictly dose-dependent for AOB and NOB. The continuous addition of 1 mg/L of erythromycin in the long-term exposure experiment made NOB to be sensitive whereas AOB to be minimally sensitive. After a prolonged exposure to concentration, even up to 50 mg/L both NOB and AOB become insensitive to increases in erythromycin. From the seven dosage levels, between 54.3% and 69.1% of erythromycin was removed by adsorption and the percentage of nitrifiers in the microbial community increased from 39.8% to 55.6%.

Original languageEnglish
Pages (from-to)337-343
Number of pages7
JournalEcological Engineering
Publication statusPublished - 2016 Sep 1


  • Adaptation
  • Erythromycin
  • Inhibition
  • Macrolide
  • Nitrification

ASJC Scopus subject areas

  • Environmental Engineering
  • Nature and Landscape Conservation
  • Management, Monitoring, Policy and Law


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