Influences of protein ingestion on glucagon-like peptide (GLP)-1-immunoreactive endocrine cells in the chicken ileum

Mohammad M. Monir, Kohzy Hiramatsu, Sachiko Matsumoto, Kei Nishimura, Chihiro Takemoto, Tomomi Shioji, Takafumi Watanabe, Kazumi Kita, Shinichi Yonekura, Sang Gun Roh

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Influences of a specific dietary nutrient on glucagon-like peptide (GLP)-1-containing cells in the chicken intestine are not yet clear. Significance of dietary protein level on GLP-1-containing cells in the chicken ileum was investigated. Chickens fed control or experimental diets of varying protein levels were examined using immunohistochemical and morphometrical techniques. We show that the protein ingestion had an impact on the activities of GLP-1-immunoreactive cells in the chicken ileum. Weight gains declined with decreasing dietary crude protein (CP) levels, but no significant differences were detected in the daily feed intake and villous height. GLP-1-immunoreactive cells with a round or oval shape were frequently observed in the lower CP level groups (4.5% and 0%). Frequencies of occurrence of GLP-1-immunoreactive cells were 41.1±4.1, 38.5±4, 34.8±3.1 and 34.3±3.7 (cells/mm2, mean±SD) for dietary CP level of 18%, 9%, 4.5% and 0% groups, respectively and significant differences were recognized between the control and lower CP level groups (P<0.05). Multiple regression analysis indicated a significant correlation between the daily protein intake and frequencies of occurrence of GLP-1-immunoreactive cells. The protein ingestion is one of the signals that influence GLP-1-containing cells in the chicken small intestine.

Original languageEnglish
Pages (from-to)581-587
Number of pages7
JournalAnimal Science Journal
Volume85
Issue number5
DOIs
Publication statusPublished - 2014 May

Keywords

  • Chicken
  • Glucagon-like peptide-1
  • Immunohistochemistry
  • Intestine
  • Protein ingestion

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Fingerprint Dive into the research topics of 'Influences of protein ingestion on glucagon-like peptide (GLP)-1-immunoreactive endocrine cells in the chicken ileum'. Together they form a unique fingerprint.

  • Cite this

    Monir, M. M., Hiramatsu, K., Matsumoto, S., Nishimura, K., Takemoto, C., Shioji, T., Watanabe, T., Kita, K., Yonekura, S., & Roh, S. G. (2014). Influences of protein ingestion on glucagon-like peptide (GLP)-1-immunoreactive endocrine cells in the chicken ileum. Animal Science Journal, 85(5), 581-587. https://doi.org/10.1111/asj.12177