Influence of total biliary diversion on the pancreatic exocrine secretion and pancreatic growth in dogs

M. Takahashi, I. Sasaki, H. Naito, C. Shibata, T. Doi, S. Matsuno

Research output: Contribution to journalArticlepeer-review

Abstract

Chronic Total Biliary Diversion induced both pancreatic trophic effect and exocrine pancreatic hypersecretion coincided with augmented plasma CCK levels. Intravenous CCK receptor antagonist (CR 1505) administration suppressed Na oleate stimulated exocrine pancreatic secretion in TBD dogs. We conclude that intraluminal bile will regulate exocrine pancreatic secretion and may affect pancreatic growth by regulating CCK release in dogs.

Original languageEnglish
Pages (from-to)391-396
Number of pages6
JournalBiomedical Research
Volume16
Issue numberSUPPL. 2
Publication statusPublished - 1995 Jan 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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