Chronic Total Biliary Diversion induced both pancreatic trophic effect and exocrine pancreatic hypersecretion coincided with augmented plasma CCK levels. Intravenous CCK receptor antagonist (CR 1505) administration suppressed Na oleate stimulated exocrine pancreatic secretion in TBD dogs. We conclude that intraluminal bile will regulate exocrine pancreatic secretion and may affect pancreatic growth by regulating CCK release in dogs.
|Number of pages||6|
|Issue number||SUPPL. 2|
|Publication status||Published - 1995|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)