Influence of Fe addition to hydroxyapatite by aqueous solution process

Mitsutaka Sato, Atsushi Nakahira

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Development of non toxic magnetic beads has been strongly desired to cure more effectively for patients having diseases such as cancer and osteosarcoma. In this study, Fe was added during calcium phosphate preparation by conventional wet process, and the condition of Fe ion and the effect of Fe doping on the crystal phase, microstructure and other properties of HAp were investigated. The crystal phase of obtained samples had a HAp structure with low crystallinity, and the crystallinity of samples decreased with increasing the Fe ratio. The obtained powders had granular crystals with 10nm in diameter. From the XRD and XANES measurement, it is thought that the actual doped amount into the HAp structure was 1, 1.8 and 3mol% for Ca of HAp in the case of 5, 10 and 20mol% of addition, respectively, and the most of added Fe existed as an iron oxide phase at the surface of HAp particles.

Original languageEnglish
Pages (from-to)422-425
Number of pages4
JournalJournal of the Ceramic Society of Japan
Volume121
Issue number1413
DOIs
Publication statusPublished - 2013 May

Keywords

  • Drug delivery system
  • Fe-doped hydroxyapatite
  • Magnetic property
  • XAFS

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemistry(all)
  • Condensed Matter Physics
  • Materials Chemistry

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