Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams

M. Kawashita; R. Araki; G. H. Takaoka

doi:10.1016/j.actbio.2008.08.018

Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams

M. Kawashita, R. Araki, G. H. Takaoka

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Silicone elastomer substrates were irradiated with acceleration voltages ranging from 3 to 9 kV and doses ranging from 1 × 10¹⁴ to 2.5 × 10¹⁵ ions cm^-2 by the simultaneous use of oxygen cluster and monomer (O₂ CM) ion beams, and then soaking in CaCl₂ solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF). Silicon oxide clusters (SiO_x) were formed at the silicone elastomer surfaces and the hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated silicone elastomer substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O₂ CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer substrates.

Original language	English
Pages (from-to)	621-627
Number of pages	7
Journal	Acta Biomaterialia
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/j.actbio.2008.08.018
Publication status	Published - 2009 Feb
Externally published	Yes

Keywords

Bioactivity
Ion beam
SBF (simulated body fluid)
Silicone elastomer
Surface modification

ASJC Scopus subject areas

Biotechnology
Biomaterials
Biochemistry
Biomedical Engineering
Molecular Biology

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10.1016/j.actbio.2008.08.018

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title = "Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams",

abstract = "Silicone elastomer substrates were irradiated with acceleration voltages ranging from 3 to 9 kV and doses ranging from 1 × 1014 to 2.5 × 1015 ions cm-2 by the simultaneous use of oxygen cluster and monomer (O2 CM) ion beams, and then soaking in CaCl2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF). Silicon oxide clusters (SiOx) were formed at the silicone elastomer surfaces and the hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated silicone elastomer substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O2 CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer substrates.",

keywords = "Bioactivity, Ion beam, SBF (simulated body fluid), Silicone elastomer, Surface modification",

author = "M. Kawashita and R. Araki and Takaoka, {G. H.}",

note = "Funding Information: This work was partially supported by a Grant-in-Aid for Young Scientists (A), Funds for Promoting Science and Technology under the Program for Exploring Advanced Interdisciplinary Frontiers, the Ministry of Education, Culture, Sports, Science and Technology, Japan, Nippon Sheet Glass Foundation for Materials Science and Engineering, Japan, and the Nanotechnology Support Project of the Ministry of Education, Culture, Sports, Science and Technology, Japan.",

year = "2009",

month = feb,

doi = "10.1016/j.actbio.2008.08.018",

language = "English",

volume = "5",

pages = "621--627",

journal = "Acta Biomaterialia",

issn = "1742-7061",

publisher = "Elsevier BV",

number = "2",

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TY - JOUR

T1 - Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams

AU - Kawashita, M.

AU - Araki, R.

AU - Takaoka, G. H.

N1 - Funding Information: This work was partially supported by a Grant-in-Aid for Young Scientists (A), Funds for Promoting Science and Technology under the Program for Exploring Advanced Interdisciplinary Frontiers, the Ministry of Education, Culture, Sports, Science and Technology, Japan, Nippon Sheet Glass Foundation for Materials Science and Engineering, Japan, and the Nanotechnology Support Project of the Ministry of Education, Culture, Sports, Science and Technology, Japan.

PY - 2009/2

Y1 - 2009/2

N2 - Silicone elastomer substrates were irradiated with acceleration voltages ranging from 3 to 9 kV and doses ranging from 1 × 1014 to 2.5 × 1015 ions cm-2 by the simultaneous use of oxygen cluster and monomer (O2 CM) ion beams, and then soaking in CaCl2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF). Silicon oxide clusters (SiOx) were formed at the silicone elastomer surfaces and the hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated silicone elastomer substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O2 CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer substrates.

AB - Silicone elastomer substrates were irradiated with acceleration voltages ranging from 3 to 9 kV and doses ranging from 1 × 1014 to 2.5 × 1015 ions cm-2 by the simultaneous use of oxygen cluster and monomer (O2 CM) ion beams, and then soaking in CaCl2 solution. The apatite-forming ability of the substrates was examined using a metastable calcium phosphate solution that had 1.5 times the ion concentrations of normal simulated body fluid (1.5SBF). Silicon oxide clusters (SiOx) were formed at the silicone elastomer surfaces and the hydrophilicity of the substrates was remarkably improved by the irradiation. The irradiated silicone elastomer substrates formed apatite in 1.5SBF, whereas unirradiated ones did not. These results suggest that irradiation using O2 CM ion beams is effective for inducing an apatite-forming ability on silicone elastomer substrates.

KW - Bioactivity

KW - Ion beam

KW - SBF (simulated body fluid)

KW - Silicone elastomer

KW - Surface modification

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Induction of bioactivity on silicone elastomer by simultaneous irradiation of oxygen cluster and monomer ion beams

Abstract

Keywords

ASJC Scopus subject areas

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