Individualized radical hysterectomy procedure using intraoperative electrical stimulation for patients with cervical cancer

Tomoyuki Nagai, Hitoshi Niikura, Hiroki Kurosawa, Sota Tanaka, Takeo Otsuki, Hiroki Utunomiya, Satoru Nagase, Tadao Takano, Kiyoshi Ito, Yasuhiro Kaiho, Haruo Nakagawa, Yoichi Arai, Nobuo Yaegashi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: In this study, by monitoring the varied distributions of nerve fascicles using intraoperative electrical stimulation (IES), we sought to establish an individualized operation based on the patient's unique nerve distribution pattern, and to determine whether this technique would result in a higher preservation rate. Materials/Methods: Radical hysterectomy was performed from 2002 to 2010. Patients in group A are the 48 cases from 2002 to 2007 in which nerve-sparing radical hysterectomy using IES as our previous report was performed. Patients in group B are the 38 cases from 2008 to 2010 in which we used our new method, which was individualized to each patient. Urodynamic study (UDS) was used to confirm nerve preservation. Nerve preservation was defined as confirming distinct detrusor contraction during urinary voiding. Results: In group B, nerve preservation rate was higher than in group A (75% vs 90%, P = 0.067). We classified the case-by-case nerve anatomy as whether the nerve fascicle was mainly on the medial side or on the lateral side of the deep uterine vein. The lateral type anatomy was observed unilaterally in 6 cases and bilaterally in 1 case. In summary, the lateral type anatomy was observed in 8 (29%) of 28 sides. In the cases evaluated by UDS, the positive predictive value of IES was 95% in group A and 100% in group B. Conclusions: Our method of IES showed a high positive predictive value of nerve preservation as confirmed by UDS. By delineating the nerve tract in detail using IES, it is possible to individualize the operation based on each patient's anatomy, with an improved nerve preservation rate.

Original languageEnglish
Pages (from-to)1591-1596
Number of pages6
JournalInternational Journal of Gynecological Cancer
Volume22
Issue number9
DOIs
Publication statusPublished - 2012 Nov 1

Keywords

  • Cervical cancer
  • Intraoperative electrical stimulation
  • Nerve-sparing radical hysterectomy
  • Urodynamic study

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology

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