In vivo physiological saline-infused hepatic vessel imaging using a two-crystal-interferometer-based phase-contrast X-ray technique

Tohoru Takeda, Akio Yoneyama, Jin Wu, Thet-Thet-Lwin, Atsushi Momose, Kazuyuki Hyodo

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Using a two-crystal-interferometer-based phase-contrast X-ray imaging system, the portal vein, capillary vessel area and hepatic vein of live rats were revealed sequentially by injecting physiological saline via the portal vein. Vessels greater than 0.06 mm in diameter were clearly shown with low levels of X-rays (552 μGy). This suggests that in vivo vessel imaging of small animals can be performed as conventional angiography without the side effects of the presently used iodine contrast agents.

Original languageEnglish
Pages (from-to)252-256
Number of pages5
JournalJournal of Synchrotron Radiation
Volume19
Issue number2
DOIs
Publication statusPublished - 2012 Mar 1
Externally publishedYes

Keywords

  • in vivo hepatic vessel imaging
  • phase-contrast X-ray technique
  • physiological saline
  • two-crystal interferometer

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Instrumentation

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