An in vitro experiment was undertaken to investigate the physiological role of estrogen on the neuromechanism, especially the release of eggs induced by serotonin, in the ovary of the scallop Patinopecten yessoensis. Estradiol-17/S (E2) had no direct action on the release of eggs from the ovarian pieces, whereas preincubation with Eg accelerated the release of eggs induced by incubation with 10~7M and 10”8 m serotonin (5-HT), depending upon the E2 concentration. In addition, the accelerating effect of E2 was inhibited with aspirin (cyclooxygenase inhibitor) and actinomycin D (RNA synthesis inhibitor). Therefore, it was suggested that prostaglandin (PG), functioning as a neuromodulator on the 5-HT action in the spawning of the scallop, is one of the factors which cause the promoting effect of F,2 on 5-HT action, together with the induction of a protein formation via a genomic action, and that E2may enhance the sensitivity to external stimuli in egg release with the progressing maturity of the scallop.
ASJC Scopus subject areas
- Aquatic Science