In vitro confocal micro-PIV measurements of blood flow in a square microchannel: The effect of the haematocrit on instantaneous velocity profiles

Rui Lima, Shigeo Wada, Motohiro Takeda, Ken ichi Tsubota, Takami Yamaguchi

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)

Abstract

A confocal microparticle image velocimetry (micro-PIV) system was used to obtain detailed information on the velocity profiles for the flow of pure water (PW) and in vitro blood (haematocrit up to 17%) in a 100-μm-square microchannel. All the measurements were made in the middle plane of the microchannel at a constant flow rate and low Reynolds number (Re=0.025). The averaged ensemble velocity profiles were found to be markedly parabolic for all the working fluids studied. When comparing the instantaneous velocity profiles of the three fluids, our results indicated that the profile shape depended on the haematocrit. Our confocal micro-PIV measurements demonstrate that the root mean square (RMS) values increase with the haematocrit implying that it is important to consider the information provided by the instantaneous velocity fields, even at low Re. The present study also examines the potential effect of the RBCs on the accuracy of the instantaneous velocity measurements.

Original languageEnglish
Pages (from-to)2752-2757
Number of pages6
JournalJournal of Biomechanics
Volume40
Issue number12
DOIs
Publication statusPublished - 2007

Keywords

  • Confocal micro-PIV
  • Haematocrit
  • Instantaneous velocity profiles
  • Microcirculation
  • Red blood cells

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

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