In vitro antimicrobial activity of hapa-B

Seiichi Aonuma; Reiko Ono; Noriko Otani; Kikuo Onuma; Akira Watanabe; Masako Sasaki; Kotaro Oizumi; Kiyoshi Konno

doi:10.11250/chemotherapy1953.33.Supplement5_149

In vitro antimicrobial activity of hapa-B

Seiichi Aonuma, Reiko Ono, Noriko Otani, Kikuo Onuma, Akira Watanabe, Masako Sasaki, Kotaro Oizumi, Kiyoshi Konno

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.

Original language	English
Pages (from-to)	149-157
Number of pages	9
Journal	Chemotherapy
Volume	33
DOIs	https://doi.org/10.11250/chemotherapy1953.33.Supplement5_149
Publication status	Published - 1985 Jan 1

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology
Drug Discovery
Oncology

Access to Document

10.11250/chemotherapy1953.33.Supplement5_149

Fingerprint Dive into the research topics of 'In vitro antimicrobial activity of hapa-B'. Together they form a unique fingerprint.

Cite this

@article{2fda12a22cee47fbb344113af20b6edc,

title = "In vitro antimicrobial activity of hapa-B",

abstract = "In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.",

author = "Seiichi Aonuma and Reiko Ono and Noriko Otani and Kikuo Onuma and Akira Watanabe and Masako Sasaki and Kotaro Oizumi and Kiyoshi Konno",

year = "1985",

month = jan,

day = "1",

doi = "10.11250/chemotherapy1953.33.Supplement5_149",

language = "English",

volume = "33",

pages = "149--157",

journal = "CHEMOTHERAPY",

issn = "0009-3165",

}

TY - JOUR

T1 - In vitro antimicrobial activity of hapa-B

AU - Aonuma, Seiichi

AU - Ono, Reiko

AU - Otani, Noriko

AU - Onuma, Kikuo

AU - Watanabe, Akira

AU - Sasaki, Masako

AU - Oizumi, Kotaro

AU - Konno, Kiyoshi

PY - 1985/1/1

Y1 - 1985/1/1

N2 - In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.

AB - In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.

UR - http://www.scopus.com/inward/record.url?scp=0022407983&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022407983&partnerID=8YFLogxK

U2 - 10.11250/chemotherapy1953.33.Supplement5_149

DO - 10.11250/chemotherapy1953.33.Supplement5_149

M3 - Article

AN - SCOPUS:0022407983

VL - 33

SP - 149

EP - 157

JO - CHEMOTHERAPY

JF - CHEMOTHERAPY

SN - 0009-3165

ER -