TY - JOUR
T1 - In vitro antimicrobial activity of hapa-B
AU - Aonuma, Seiichi
AU - Ono, Reiko
AU - Otani, Noriko
AU - Onuma, Kikuo
AU - Watanabe, Akira
AU - Sasaki, Masako
AU - Oizumi, Kotaro
AU - Konno, Kiyoshi
PY - 1985/1/1
Y1 - 1985/1/1
N2 - In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.
AB - In vitro antimicrobial activity of hapa-B, a new derivative of aminoglycoside, was examined by a broth dilution method with Dynatech MIC 2000 system. The minimum inhibitory concentrations of hapa-B were compared with those of gentamicin (GM) and amikacin (AMK) against the following 120 strains (each 20 strains) of clinical isolates of 5. aureus, E. coli, K. pneumoniae, S. marcescens, Enterobacter spieces and P. aeruginosa. Against S. aureus, E. coli, K. pneumoniae and S. marcescens, hapa-B was shown to be less active than GM, but more active than AMK. hapa-B was as active as AMK, although less active than GM, against Enterobacter spieces and P. aeruginosa.
UR - http://www.scopus.com/inward/record.url?scp=0022407983&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022407983&partnerID=8YFLogxK
U2 - 10.11250/chemotherapy1953.33.Supplement5_149
DO - 10.11250/chemotherapy1953.33.Supplement5_149
M3 - Article
AN - SCOPUS:0022407983
VL - 33
SP - 149
EP - 157
JO - CHEMOTHERAPY
JF - CHEMOTHERAPY
SN - 0009-3165
ER -
