In vitro and in vivo evaluation of hydroxyapatite block and granules supported with wheat starch set through the process of hydration under a physiological condition

Toshitake Furusawa; Ikue Oshino; Kakeru Yoshida; Naho Oshiyama; Takahiro Kawai; Masaaki Sato; Toshimitsu Okudera

doi:10.1246/cl.121243

In vitro and in vivo evaluation of hydroxyapatite block and granules supported with wheat starch set through the process of hydration under a physiological condition

Toshitake Furusawa, Ikue Oshino, Kakeru Yoshida, Naho Oshiyama, Takahiro Kawai, Masaaki Sato, Toshimitsu Okudera

Frontier Research Institute of Interdisciplinary Sciences (FRIS)

Research output: Contribution to journal › Article › peer-review

Abstract

Needle-like hydroxyapatites obtained through a hydration reaction process between anhydrous dicalcium phosphate (ADCP) and tetracalcium phosphate (TTCP) were reinforced with wheat starch to form composite blocks, and they showed mechanical properties corresponding to their compositions: mass fraction of calcium phosphate powders/starch solution and starch concentration. A kind of the composite granules was found to be osteoconductive in an in vivo examination with a rat model.

Original language	English
Pages (from-to)	507-508
Number of pages	2
Journal	Chemistry Letters
Volume	42
Issue number	5
DOIs	https://doi.org/10.1246/cl.121243
Publication status	Published - 2013 May 15

ASJC Scopus subject areas

Chemistry(all)

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In vitro and in vivo evaluation of hydroxyapatite block and granules supported with wheat starch set through the process of hydration under a physiological condition. / Furusawa, Toshitake; Oshino, Ikue; Yoshida, Kakeru; Oshiyama, Naho; Kawai, Takahiro; Sato, Masaaki; Okudera, Toshimitsu.

In: Chemistry Letters, Vol. 42, No. 5, 15.05.2013, p. 507-508.

Research output: Contribution to journal › Article › peer-review

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AU - Furusawa, Toshitake

AU - Oshino, Ikue

AU - Yoshida, Kakeru

AU - Oshiyama, Naho

AU - Kawai, Takahiro

AU - Sato, Masaaki

AU - Okudera, Toshimitsu

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AB - Needle-like hydroxyapatites obtained through a hydration reaction process between anhydrous dicalcium phosphate (ADCP) and tetracalcium phosphate (TTCP) were reinforced with wheat starch to form composite blocks, and they showed mechanical properties corresponding to their compositions: mass fraction of calcium phosphate powders/starch solution and starch concentration. A kind of the composite granules was found to be osteoconductive in an in vivo examination with a rat model.

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In vitro and in vivo evaluation of hydroxyapatite block and granules supported with wheat starch set through the process of hydration under a physiological condition

Abstract

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