Impurity-induced defect and its effect on protein crystal perfection

Izumi Yoshizaki, Seijiro Fukuyama, Haruhiko Koizumi, Masaru Tachibana, Kenichi Kojima, Yoshiki Matsuura, Masahiko Tanaka, Noriyuki Igarashi, Akio Kadowaki, Long Rong, Satoshi Adachi, Shinichi Yoda, Hiroshi Komatsu

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


The rocking curve widths of tetragonal lysozyme crystals were measured. Typical full-width half-maximum (FWHM) of the rocking curve of crystals grown from a pure lysozyme solution were 0.004-0.006°, while those crystals containing 5% lysozyme dimer were 0.006-0.010°. X-ray topography experiments revealed that dislocations existed in crystals containing the lysozyme dimer. These dislocations are one of the causes of rocking curve width broadening. 2×104 cm-2 pits were observed on the {1 0 1} face in contaminated crystals, but few, if any pits were observed in either face of the pure crystals.

Original languageEnglish
Pages (from-to)185-191
Number of pages7
JournalJournal of Crystal Growth
Issue number1
Publication statusPublished - 2006 Apr 15
Externally publishedYes


  • A1. Biocrystallization
  • A1. Defects
  • A1. Etching
  • A1. Impurities
  • A1. X-ray Topography
  • B1. Lysozyme

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Inorganic Chemistry
  • Materials Chemistry


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