We have reported attempts to trap microcbubbles by ultrasound to increase density of microbubbles considering therapeutic efficiency. Because the form of blood vessel is complex, therapeutic efficiency will be improved by trapping in multiple areas simultaneously. However, there is a limitation of the number of transducers on body surface. In this study, we have developed a 2D-array transducer to form multiple focal points by designing the waveform. We observed microbubbles were trapped in 4 paths as shown in the figure. From the results, we confirmed the trapping efficiency was improved by comparing with the experiment of continuous emission with the same ultrasound energy above.
|Journal||Transactions of Japanese Society for Medical and Biological Engineering|
|Publication status||Published - 2014 Aug 17|
- Drug delivery system
ASJC Scopus subject areas
- Biomedical Engineering