Improved Syntheses of (+)-Iridomyrmecin and (-)-Isoiridomyrmecin, Major Components of Matatabilactone

Masaatsu Adachi, Yu Miyazawa, Toshio Nishikawa

Research output: Contribution to journalArticle

Abstract

Improved syntheses of iridomyrmecin and isoiridomyrmecin, major components of matatabilactone, are described. The synthesis features a direct transformation of nepetalactol into key intermediates by DIBAL-H reduction and provides an expeditious and straightforward production of iridoid lactones for biological investigations of the Matatabi phenomenon.

Original languageEnglish
Pages (from-to)883-886
Number of pages4
JournalNatural product communications
Volume11
Issue number7
DOIs
Publication statusPublished - 2016 Jan 1
Externally publishedYes

Keywords

  • Iridoid
  • Iridomyrmecin
  • Isoiridomyrmecin
  • Matatabilactone

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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