Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest

Yusuke Takagi, Satoshi Yasuda, Jun Takahashi, Morihiko Takeda, Masaharu Nakayama, Kenta Ito, Masanori Hirose, Yuji Wakayama, Koji Fukuda, Hiroaki Shimokawa

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

Background: The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated. Methods and Results: Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient. Conclusions: OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary.

Original languageEnglish
Pages (from-to)767-769
Number of pages3
JournalCirculation Journal
Volume73
Issue number4
DOIs
Publication statusPublished - 2009 Apr

Keywords

  • Coronary vasospasm
  • Electrophysiology
  • Sudden cardiac death

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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