Impacts of genotyping strategies on long-term genetic response in genomic selection

Motohide Nishio, Masahiro Satoh

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The present study investigated the effects of the choices of animals of reference populations on long-term responses to genomic selection. Simulated populations comprised 300 individuals and 10 generations of selection practiced for a trait with heritability of 0.1, 0.3 or 0.5. Thirty individuals were randomly selected in the first five generations and selected by estimated breeding values from best linear unbiased prediction (BLUP) and genomic BLUP in the subsequent five generations. The reference populations comprise all animals for all generations (scenario 1), all animals for 6-10 generations (scenario 2) and 2-6 generations (scenario 3), and half of the animals for all generations (scenario 4). For all heritability levels, the genetic gains in generation 10 were similar in scenarios 1 and 2. Among scenarios 2 to 4, the highest genetic gains were obtained in scenario 2, with heritabilities of 0.1 and 0.3 as well as scenario 4 with heritability of 0.5. The inbreeding coefficients in scenarios 1, 2 and 4 were lower than those in BLUP, especially within cases with low heritability. These results indicate an appropriate choice of reference population can improve genetic gain and restrict inbreeding even when the reference population size is limited.

Original languageEnglish
Pages (from-to)511-516
Number of pages6
JournalAnimal Science Journal
Volume85
Issue number5
DOIs
Publication statusPublished - 2014 May
Externally publishedYes

Keywords

  • Genomic selection
  • Long-term
  • Reference population
  • Selection response

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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