Immunohistological evaluation of Creutzfeldt-Jakob disease with reference to the type PrP(res) deposition

J. Tateishi, T. Kitamoto, H. Kretzschmar, P. Mehraein

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

German patients suspected of having Creutzfeldt-Jakob disease (CJD) and related diseases were studied pathologically. The immunohistochemical findings after hydrolytic autoclaving pretreatment sensitively detected the synaptic-type deposition of the protease-resistant isoform of the prion protein (PrP(res)) which thus served to establish the consensus diagnosis of CJD.

Original languageEnglish
Pages (from-to)358-360
Number of pages3
JournalClinical Neuropathology
Volume15
Issue number6
Publication statusPublished - 1996 Nov

Keywords

  • Creutzfeldt-Jakob disease
  • Hydrolytic autoclaving pretreatment
  • Immunohistochemistry
  • Prions

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Neurology
  • Clinical Neurology

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