TY - JOUR
T1 - Immunohistochemical Analysis of the Harbor Porpoise Using Antipodoplanin Antibody PMab-237
AU - Yamada, Shinji
AU - Itai, Shunsuke
AU - Nakamura, Takuro
AU - Takei, Junko
AU - Sano, Masato
AU - Konnai, Satoru
AU - Kobayashi, Atsushi
AU - Nakagun, Shotaro
AU - Kobayashi, Yoshiyasu
AU - Kaneko, Mika K.
AU - Kato, Yukinari
N1 - Publisher Copyright:
© 2019, Mary Ann Liebert, Inc., publishers 2019.
PY - 2019/6
Y1 - 2019/6
N2 - Podoplanin (PDPN)/T1 alpha is known as a specific marker of lymphatic endothelial cells and type I alveolar cells. Sensitive and specific monoclonal antibodies (mAbs) for PDPN are needed for immunohistochemical analyses. Recently, we developed an anticetacean PDPN mAb, PMab-237. Herein, immunohistochemical analyses showed that PMab-237 strongly detected pulmonary type I alveolar cells, renal podocytes, and lymphatic endothelial cells of the harbor porpoise. These findings suggest that PMab-237 may be useful for immunohistochemical analyses for cetacean tissues.
AB - Podoplanin (PDPN)/T1 alpha is known as a specific marker of lymphatic endothelial cells and type I alveolar cells. Sensitive and specific monoclonal antibodies (mAbs) for PDPN are needed for immunohistochemical analyses. Recently, we developed an anticetacean PDPN mAb, PMab-237. Herein, immunohistochemical analyses showed that PMab-237 strongly detected pulmonary type I alveolar cells, renal podocytes, and lymphatic endothelial cells of the harbor porpoise. These findings suggest that PMab-237 may be useful for immunohistochemical analyses for cetacean tissues.
KW - PDPN
KW - PMab-237
KW - cetacean podoplanin
KW - lymphatic endothelial cells
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U2 - 10.1089/mab.2019.0014
DO - 10.1089/mab.2019.0014
M3 - Article
C2 - 31161964
AN - SCOPUS:85067304351
VL - 38
SP - 104
EP - 107
JO - Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
JF - Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
SN - 2167-9436
IS - 3
ER -