Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity

Liushiqi Borjigin; Tomoyuki Shimazu; Yuki Katayama; Meihua Li; Takumi Satoh; Kouichi Watanabe; Haruki Kitazawa; Sang gun Roh; Hisashi Aso; Kazuo Katoh; Takafumi Uchida; Yoshihito Suda; Akiko Sakuma; Mituru Nakajo; Keiichi Suzuki

doi:10.1111/asj.12471

Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity

Liushiqi Borjigin, Tomoyuki Shimazu, Yuki Katayama, Meihua Li, Takumi Satoh, Kouichi Watanabe, Haruki Kitazawa, Sang gun Roh, Hisashi Aso, Kazuo Katoh, Takafumi Uchida, Yoshihito Suda, Akiko Sakuma, Mituru Nakajo, Keiichi Suzuki

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5 Citations (Scopus)

Abstract

Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions were compared between the immunity-selected Large White line and the non-selected Large White line. The selected Large White line showed a higher level of pulmonary MPS lesions compared with the non-selected Large White line. Subsequent to vaccination, the percentage of natural killer cells and T cells (CD3⁺CD4⁺CD8^- and CD3⁺CD4^-CD8⁺ T cells) were significantly increased in the non-selected line but remained unchanged in the immunity-selected Large White line. Secretion of Mycoplasma hyopneumoniae vaccine-specific immunoblogulin G and phagocyte activity in peripheral blood were significantly higher in the immunity-selected Large White line than in the non-selected line. Expression of interleukin (IL)-4 and IL-6 messenger RNA in hilar lymph nodes was significantly lower in the immunity-selected Large White line than in the non-selected line. However, expression of IL-10 in all immune tissues was significantly higher in the immunity-selected Large White line. These results suggest that the selection for high immunity was not effective in increasing resistance to MPS lung lesions.

Original language	English
Pages (from-to)	638-645
Number of pages	8
Journal	Animal Science Journal
Volume	87
Issue number	5
DOIs	https://doi.org/10.1111/asj.12471
Publication status	Published - 2016 May 1

Keywords

Disease resistance
Immunogenic property
Mycoplasmal pneumonia lesion
Pig

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/asj.12471

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Borjigin, L., Shimazu, T., Katayama, Y., Li, M., Satoh, T., Watanabe, K., Kitazawa, H., Roh, S. G., Aso, H., Katoh, K., Uchida, T., Suda, Y., Sakuma, A., Nakajo, M., & Suzuki, K. (2016). Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity. Animal Science Journal, 87(5), 638-645. https://doi.org/10.1111/asj.12471

Borjigin, L, Shimazu, T, Katayama, Y, Li, M, Satoh, T, Watanabe, K, Kitazawa, H , Roh, SG , Aso, H, Katoh, K, Uchida, T, Suda, Y, Sakuma, A, Nakajo, M & Suzuki, K 2016, 'Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity', Animal Science Journal, vol. 87, no. 5, pp. 638-645. https://doi.org/10.1111/asj.12471

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title = "Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity",

abstract = "Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions were compared between the immunity-selected Large White line and the non-selected Large White line. The selected Large White line showed a higher level of pulmonary MPS lesions compared with the non-selected Large White line. Subsequent to vaccination, the percentage of natural killer cells and T cells (CD3+CD4+CD8- and CD3+CD4-CD8+ T cells) were significantly increased in the non-selected line but remained unchanged in the immunity-selected Large White line. Secretion of Mycoplasma hyopneumoniae vaccine-specific immunoblogulin G and phagocyte activity in peripheral blood were significantly higher in the immunity-selected Large White line than in the non-selected line. Expression of interleukin (IL)-4 and IL-6 messenger RNA in hilar lymph nodes was significantly lower in the immunity-selected Large White line than in the non-selected line. However, expression of IL-10 in all immune tissues was significantly higher in the immunity-selected Large White line. These results suggest that the selection for high immunity was not effective in increasing resistance to MPS lung lesions.",

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author = "Liushiqi Borjigin and Tomoyuki Shimazu and Yuki Katayama and Meihua Li and Takumi Satoh and Kouichi Watanabe and Haruki Kitazawa and Roh, {Sang gun} and Hisashi Aso and Kazuo Katoh and Takafumi Uchida and Yoshihito Suda and Akiko Sakuma and Mituru Nakajo and Keiichi Suzuki",

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AU - Borjigin, Liushiqi

AU - Shimazu, Tomoyuki

AU - Katayama, Yuki

AU - Li, Meihua

AU - Satoh, Takumi

AU - Watanabe, Kouichi

AU - Kitazawa, Haruki

AU - Roh, Sang gun

AU - Aso, Hisashi

AU - Katoh, Kazuo

AU - Uchida, Takafumi

AU - Suda, Yoshihito

AU - Sakuma, Akiko

AU - Nakajo, Mituru

AU - Suzuki, Keiichi

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N2 - Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions were compared between the immunity-selected Large White line and the non-selected Large White line. The selected Large White line showed a higher level of pulmonary MPS lesions compared with the non-selected Large White line. Subsequent to vaccination, the percentage of natural killer cells and T cells (CD3+CD4+CD8- and CD3+CD4-CD8+ T cells) were significantly increased in the non-selected line but remained unchanged in the immunity-selected Large White line. Secretion of Mycoplasma hyopneumoniae vaccine-specific immunoblogulin G and phagocyte activity in peripheral blood were significantly higher in the immunity-selected Large White line than in the non-selected line. Expression of interleukin (IL)-4 and IL-6 messenger RNA in hilar lymph nodes was significantly lower in the immunity-selected Large White line than in the non-selected line. However, expression of IL-10 in all immune tissues was significantly higher in the immunity-selected Large White line. These results suggest that the selection for high immunity was not effective in increasing resistance to MPS lung lesions.

AB - Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions were compared between the immunity-selected Large White line and the non-selected Large White line. The selected Large White line showed a higher level of pulmonary MPS lesions compared with the non-selected Large White line. Subsequent to vaccination, the percentage of natural killer cells and T cells (CD3+CD4+CD8- and CD3+CD4-CD8+ T cells) were significantly increased in the non-selected line but remained unchanged in the immunity-selected Large White line. Secretion of Mycoplasma hyopneumoniae vaccine-specific immunoblogulin G and phagocyte activity in peripheral blood were significantly higher in the immunity-selected Large White line than in the non-selected line. Expression of interleukin (IL)-4 and IL-6 messenger RNA in hilar lymph nodes was significantly lower in the immunity-selected Large White line than in the non-selected line. However, expression of IL-10 in all immune tissues was significantly higher in the immunity-selected Large White line. These results suggest that the selection for high immunity was not effective in increasing resistance to MPS lung lesions.

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KW - Mycoplasmal pneumonia lesion

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Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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