Abstract
Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions were compared between the immunity-selected Large White line and the non-selected Large White line. The selected Large White line showed a higher level of pulmonary MPS lesions compared with the non-selected Large White line. Subsequent to vaccination, the percentage of natural killer cells and T cells (CD3+CD4+CD8- and CD3+CD4-CD8+ T cells) were significantly increased in the non-selected line but remained unchanged in the immunity-selected Large White line. Secretion of Mycoplasma hyopneumoniae vaccine-specific immunoblogulin G and phagocyte activity in peripheral blood were significantly higher in the immunity-selected Large White line than in the non-selected line. Expression of interleukin (IL)-4 and IL-6 messenger RNA in hilar lymph nodes was significantly lower in the immunity-selected Large White line than in the non-selected line. However, expression of IL-10 in all immune tissues was significantly higher in the immunity-selected Large White line. These results suggest that the selection for high immunity was not effective in increasing resistance to MPS lung lesions.
Original language | English |
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Pages (from-to) | 638-645 |
Number of pages | 8 |
Journal | Animal Science Journal |
Volume | 87 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2016 May 1 |
Keywords
- Disease resistance
- Immunogenic property
- Mycoplasmal pneumonia lesion
- Pig
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)