TY - JOUR
T1 - Imaging the pyramidal tract in patients with brain tumors
AU - Inoue, Takashi
AU - Shimizu, Hiroaki
AU - Yoshimoto, Takashi
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1999/3
Y1 - 1999/3
N2 - The clinical usefulness of diffusion-weighted magnetic resonance imaging (DWI) of the pyramidal tract was evaluated in patients with brain tumors. Five normal volunteers and seven patients with glioma (n=4) or meningioma (n=3) near the pyramidal tract underwent coronal echo planar DWI. Greyscale DWIs in each of the three orthogonal diffusion gradients were transformed into graduations, color-coded as red, green or blue, respectively, and then composited to form a combined color image. The entire pyramidal tract was visualized on a single fiber mapping image by combining the upper half of the image slice including the primary motor cortex, the corona radiata and the internal capsule with the lower half of the image slice including the internal capsule, the cerebral peduncle and the ventral brain stem. Fiber mapping images demonstrated the pyramidal tract as a distinct band indicating nerve fiber integrity in all volunteers. The entire pyramidal tract from the primary motor subcortex to the ventral brain stem could be traced. Fiber mapping images showed the ipsilateral pyramidal tract as either discontinuous due to impaired anisotropy or compressed due to mass effect in patients with brain tumors. These findings corresponded well with the pre- and postoperative motor functions. Fiber mapping images are useful for evaluating the white matter neuronal tracts and can provide indications for determining surgical strategy. Copyright (C) 1999 Elsevier Science B.V.
AB - The clinical usefulness of diffusion-weighted magnetic resonance imaging (DWI) of the pyramidal tract was evaluated in patients with brain tumors. Five normal volunteers and seven patients with glioma (n=4) or meningioma (n=3) near the pyramidal tract underwent coronal echo planar DWI. Greyscale DWIs in each of the three orthogonal diffusion gradients were transformed into graduations, color-coded as red, green or blue, respectively, and then composited to form a combined color image. The entire pyramidal tract was visualized on a single fiber mapping image by combining the upper half of the image slice including the primary motor cortex, the corona radiata and the internal capsule with the lower half of the image slice including the internal capsule, the cerebral peduncle and the ventral brain stem. Fiber mapping images demonstrated the pyramidal tract as a distinct band indicating nerve fiber integrity in all volunteers. The entire pyramidal tract from the primary motor subcortex to the ventral brain stem could be traced. Fiber mapping images showed the ipsilateral pyramidal tract as either discontinuous due to impaired anisotropy or compressed due to mass effect in patients with brain tumors. These findings corresponded well with the pre- and postoperative motor functions. Fiber mapping images are useful for evaluating the white matter neuronal tracts and can provide indications for determining surgical strategy. Copyright (C) 1999 Elsevier Science B.V.
KW - Brain
KW - Diffusion
KW - Magnetic resonance imaging
KW - Pyramidal tract
KW - Tumor
UR - http://www.scopus.com/inward/record.url?scp=0032995465&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032995465&partnerID=8YFLogxK
U2 - 10.1016/S0303-8467(98)00069-9
DO - 10.1016/S0303-8467(98)00069-9
M3 - Article
C2 - 10350195
AN - SCOPUS:0032995465
VL - 101
SP - 4
EP - 10
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
SN - 0303-8467
IS - 1
ER -