Imaging studies of intraductal tubulopapillary neoplasms of the pancreas: 2-tone duct sign and cork-of-wine-bottle sign as indicators of intraductal tumor growth

Utaroh Motosugi, Hiroshi Yamaguchi, Toru Furukawa, Tomoaki Ichikawa, Takashi Hatori, Izumi Fujita, Masakazu Yamamoto, Fuyuhiko Motoi, Atsushi Kanno, Tomoo Watanabe, Naoto Koike, Isamu Koyama, Junya Kobayashi, Michio Shimizu

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Objective: The objective of this study was to describe the imaging findings for intraductal tubulopapillary neoplasms of the pancreas. Methods: Eleven pancreatic tumors pathologically confirmed as intraductal tubulopapillary neoplasm were retrospectively collected. The dynamic contrast-enhanced computed tomography (CT), magnetic resonance (MR) imaging including MR cholangiopancreatography (MRCP), ultrasound, and endoscopic retrograde cholangiopancreatography (ERCP) results were reviewed. The 2-tone duct sign and cork-of-wine-bottle sign were reviewed as indicators of intraductal tumor growth on CT/MR and MRCP/ERCP images, respectively. Results: A 2-tone duct sign was noted on the dynamic CT images (7/10, 70%) and on the MR imaging (5/8, 63%). The distal main pancreatic duct was dilated in all the patients except one, who had a branch duct lesion. A cork-of-wine-bottle sign was observed on the MRCP image (3/8, 38%) and on the ERCP image (3/6, 50%). Conclusions: Intraductal tubulopapillary neoplasms are rare tumors showing characteristic imaging findings such as the 2-tone duct sign and the cork-of-wine-bottle sign that represent their intraductal growth.

Original languageEnglish
Pages (from-to)710-717
Number of pages8
JournalJournal of Computer Assisted Tomography
Volume36
Issue number6
DOIs
Publication statusPublished - 2012 Nov

Keywords

  • CT
  • Intraductal tubulopapillary neoplasm
  • MR imaging
  • Pancreas
  • Tumor

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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