Identification of two cDNAs for human actin-related proteins (Arps) that have remarkable similarity to conventional actin

Masahiko Harata, Katsuhiko Nishimori, Shunsuke Hatta

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We identified two cDNAs coding for the novel human actin-related proteins (Arps) hArpM1 and hArpM2. Both of them show remarkable similarity to conventional actin, and the ATP-binding motif and nuclear-export signals of actin are highly conserved. Their mRNAs are expressed in all tested human tissues, but in smaller amounts than that of actin. These features suggest that hArpM1 and M2 are involved in cytoskeletal organization like other cytoplasmic Arp subfamilies.

Original languageEnglish
Pages (from-to)130-133
Number of pages4
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1522
Issue number2
DOIs
Publication statusPublished - 2001 Dec 3

Keywords

  • ATP binding
  • Actin-related protein
  • Nuclear export signal

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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