Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax (Addax nasomaculatus) (Subfamily Antelopinae)

Khuukhenbaatar Ganzorig, Takuya Asakawa, Masashi Sasaki, Tadao Saito, Isao Suzuki, Kenji Fukuda, Tadasu Urashima

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(α2-8)Neu5Ac(α2-3)Gal(β1-4)Glc, Neu5Gc(α2-8)Neu5Gc(α2-3)Gal(β1-4)Glc, Neu5Ac(α2-3)Gal(β1-4)Glc, Neu5Ac(α2-6)Gal(β1-4)GlcNAc, Neu5Gc(α2-3)Gal(β1-4)Glc, Neu5Gc(α2-6)Gal(β1-4)Glc, Neu5Gc(α2-6)Gal(β1-4)GlcNAc. In addition, an oligosaccharide nucleotide Neu5Gc(α2-6)Gal(β1-4)GlcNAcα1-UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared.

Original languageEnglish
Pages (from-to)167-175
Number of pages9
JournalAnimal Science Journal
Volume89
Issue number1
DOIs
Publication statusPublished - 2018 Jan

Keywords

  • Bovidae milk oligosaccharides
  • addax colostrum
  • milk sugar nucleotide
  • sialyl milk oligosaccharides

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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