Hypoxia imaging

Tomohiro Kaneta

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Tumor hypoxia is a spatially and temporally heterogeneous phenomenon, resulting from the combined effect of many factors, including tumor type and volume, disease site (specific organ or tissue), regional microvessel density, blood flow, oxygen diffusion and consumption rates, etc. Given the importance of hypoxia in cancer progression and therapy, there has been a growing impetus to develop noninvasive imaging methods to detect and assess tumor hypoxia. In this paper, we overviewed representative PET or SPECT tracers for imaging hypoxia, and clinical utilities toward tailor-made cancer therapy.

    Original languageEnglish
    Pages (from-to)529-535
    Number of pages7
    JournalJapanese Journal of Clinical Radiology
    Volume53
    Issue number4
    Publication statusPublished - 2008 May 5

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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