Abstract
We investigated morning home blood pressure (BP)- and heart rate (HR)-lowering effects of 2.5/5 mg bisoprolol in 70 patients with essential hypertension. After 4 weeks of treatment, mean home systolic/diastolic BP and HR significantly decreased by 2.6/5.2 mm Hg and by 8.1 bpm, respectively (all P < .05). The time required to reach 95% of the maximum lowering effect of bisoprolol (stabilizing time) was 5.1 days for home systolic BP (P = .2), 5.1 days for home diastolic BP (P = .0007), and 4.3 days for home HR (P < .0001). We demonstrated that the administration of low-dose bisoprolol significantly and rapidly decreased home BP and HR.
Original language | English |
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Pages (from-to) | 284-289 |
Number of pages | 6 |
Journal | Clinical and Experimental Hypertension |
Volume | 34 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2012 Jul |
Keywords
- antihypertensive drug
- bisoprolol
- home blood pressure
- home heart rate
- lowering effect
- stabilizing time
- β-blocker
ASJC Scopus subject areas
- Internal Medicine
- Physiology