Hypertrophic cranial pachymeningitis in MPO-ANCA-related vasculitis: a case report and literature review.

Kimio Watanabe; Yoshihiro Tani; Hiroshi Kimura; Jun Asai; Kenichi Tanaka; Yoshimitsu Hayashi; Koichi Asahi; Masaaki Nakayama; Tsuyoshi Watanabe

doi:10.5387/fms.59.56

Hypertrophic cranial pachymeningitis in MPO-ANCA-related vasculitis: a case report and literature review.

Kimio Watanabe, Yoshihiro Tani, Hiroshi Kimura, Jun Asai, Kenichi Tanaka, Yoshimitsu Hayashi, Koichi Asahi, Masaaki Nakayama, Tsuyoshi Watanabe

University Hospital

Research output: Contribution to journal › Review article

5 Citations (Scopus)

Abstract

A 75-year-old woman presented with rapidly progressive glomerulonephritis with positive results for anti-myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA). Corticosteroid therapy was successfully introduced. However, 7 months later, magnetic resonance imaging revealed marked swelling in the falx cerebri and high density regions were apparent on gallium scintigraphy, leading to diagnosis of hypertrophic cranial pachymeningitis (HCP). Symptoms improved with intensified corticosteroid therapy, but radiological examination 9 months later revealed right nasal sinus inflammation accompanied by osteolytic change. Granulomatosis with polyangiitis (Wegener's) was finally diagnosed. HCP is an important complication in MPO-ANCA-related vasculitis, and needs to be considered during the clinical course.

Original language	English
Pages (from-to)	56-62
Number of pages	7
Journal	Fukushima journal of medical science
Volume	59
Issue number	1
DOIs	https://doi.org/10.5387/fms.59.56
Publication status	Published - 2013

ASJC Scopus subject areas

Medicine(all)

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Watanabe, K., Tani, Y., Kimura, H., Asai, J., Tanaka, K., Hayashi, Y., Asahi, K., Nakayama, M., & Watanabe, T. (2013). Hypertrophic cranial pachymeningitis in MPO-ANCA-related vasculitis: a case report and literature review. Fukushima journal of medical science, 59(1), 56-62. https://doi.org/10.5387/fms.59.56

Hypertrophic cranial pachymeningitis in MPO-ANCA-related vasculitis : a case report and literature review. / Watanabe, Kimio; Tani, Yoshihiro; Kimura, Hiroshi; Asai, Jun; Tanaka, Kenichi; Hayashi, Yoshimitsu; Asahi, Koichi; Nakayama, Masaaki; Watanabe, Tsuyoshi.

In: Fukushima journal of medical science, Vol. 59, No. 1, 2013, p. 56-62.

Research output: Contribution to journal › Review article

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abstract = "A 75-year-old woman presented with rapidly progressive glomerulonephritis with positive results for anti-myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA). Corticosteroid therapy was successfully introduced. However, 7 months later, magnetic resonance imaging revealed marked swelling in the falx cerebri and high density regions were apparent on gallium scintigraphy, leading to diagnosis of hypertrophic cranial pachymeningitis (HCP). Symptoms improved with intensified corticosteroid therapy, but radiological examination 9 months later revealed right nasal sinus inflammation accompanied by osteolytic change. Granulomatosis with polyangiitis (Wegener's) was finally diagnosed. HCP is an important complication in MPO-ANCA-related vasculitis, and needs to be considered during the clinical course.",

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