Hydrolysis of biopex-R-allografts cement and the osteoblastic response to the cement

Takuya Nomoto; Shunro Yamaguchi; Tohru Sekino; Koichi Niihara

Hydrolysis of biopex-R-allografts cement and the osteoblastic response to the cement

Takuya Nomoto, Shunro Yamaguchi, Tohru Sekino, Koichi Niihara

Institute of Multidisciplinary Research for Advanced Materials (IMRAM)

Research output: Contribution to journal › Article › peer-review

Abstract

A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-R-allografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.

Original language	English
Pages (from-to)	76-79
Number of pages	4
Journal	Journal of Ceramic Processing Research
Volume	5
Issue number	1
Publication status	Published - 2004 Jun 8

Keywords

Allograft
Bone cement
Calcium phosphate
Cell adhesion
Octacalcium phosphate

ASJC Scopus subject areas

Ceramics and Composites

Cite this

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abstract = "A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-R-allografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.",

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AU - Nomoto, Takuya

AU - Yamaguchi, Shunro

AU - Sekino, Tohru

AU - Niihara, Koichi

PY - 2004/6/8

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N2 - A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-R-allografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.

AB - A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-R-allografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.

KW - Allograft

KW - Bone cement

KW - Calcium phosphate

KW - Cell adhesion

KW - Octacalcium phosphate

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Hydrolysis of biopex-R-allografts cement and the osteoblastic response to the cement

Abstract

Keywords

ASJC Scopus subject areas

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