Hydrolysis of biopex-R-allografts cement and the osteoblastic response to the cement

Takuya Nomoto, Shunro Yamaguchi, Tohru Sekino, Koichi Niihara

Research output: Contribution to journalArticle

Abstract

A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-R-allografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalJournal of Ceramic Processing Research
Volume5
Issue number1
Publication statusPublished - 2004 Jun 8

Keywords

  • Allograft
  • Bone cement
  • Calcium phosphate
  • Cell adhesion
  • Octacalcium phosphate

ASJC Scopus subject areas

  • Ceramics and Composites

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